Advil Pain Reliever Fever Reducer 225 Coated Tablets The pain reliever in Advil Coated Tablets is Ibuprofen, a nonsteroidal antiinflammatory drug NSAID that when taken as directed is a safe and effective pain reliever and fever reducer. No other OTC pain reliever has been proven to work faster or stronger than Advil. For over 30 years, people have chosen Advil for safe and quick relief of their acute aches and pains. Use as directed. Any medication may cause side effects. You should not take more than the recommended dose because it will increase the risk of side effects. To maximize the benefit and reduce risk, it is important to use overthecounter medicines responsibly according to the label and speak with a doctor or pharmacist if you have any questions. Please refer to the label for complete warnings and important information.